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AAC: ADP/ATP provider; mtNDPK: mitochondrial nucleoside diphosphate kinase; mtNMPK: mitochondrial nucleoside monophosphate kinase; TCA cycle: tricarboxylic acid cycle; UCP: uncoupling protein; ?: possibly direct inhibition. Representative references are cited.a, Illustration with the simulation set up accustomed to assess binding of negatively char
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fibroblasts in a very dose-dependent way. Depending on the ineffectiveness of such inhibitors on NPC1�?�?cells, we infer the clearance is due to a immediate effect on the NPC1 protein and never a standard bypass of your NPC1-dependent pathways as is found in cells treated with cholesterol-chelating cyclodextrins (sixty one).The location is prot
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